Regulatory document graphic for the WADA 2025 Prohibited List update
Effective

WADA 2025 Prohibited List now in force

The updated list, effective January 1, 2025, keeps non-approved peptides such as BPC-157 in S0 and reminds athletes that sport rules differ from drug-approval rules.

Event: 2025-01-01Published: 2025-01-03Effective: 2025-01-01

As of January 1, 2025, the WADA Prohibited List is in force. BPC-157 remains listed as an example in class S0 (non-approved substances), which is prohibited at all times for athletes subject to the World Anti-Doping Code.

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WADA's 2025 Prohibited List took effect on January 1, 2025. The list is one of eight mandatory International Standards under the World Anti-Doping Code. For peptide regulation, the most relevant class is S0: Non-Approved Substances. BPC-157 appears as an example.

It is important to distinguish WADA's sport-rule prohibition from FDA approval. A substance can be prohibited in sport without being FDA approved or unapproved in a particular way, and FDA approval does not automatically determine WADA status.

Key takeaways

  • S0 covers non-approved substances, including BPC-157.
  • WADA status is a sport rule, not an FDA approval decision.
  • Athletes are strictly liable for what is in their systems.

What changed

WADA's 2025 Prohibited List entered force, continuing the S0 classification for BPC-157.

What did not change

FDA approval status of BPC-157 did not change.

Next step

WADA will publish annual updates; athletes should verify status through GlobalDRO or their anti-doping organization.

Affected records

Controlling documents

Author: Peptide Rulebook Editorial Team
Legal reviewer: External Regulatory Reviewer
Last verified: 2025-03-01